PARAGANGLIOMA, IS IT REALLY THE BAD GUY?
DOI:
https://doi.org/10.58043/rphrc.22Abstract
Paragangliomas are rare neuroendocrine tumors that arise from the extra-adrenal sympathetic and parasympathetic paraganglia. Most parasympathetic paragangliomas are nonfunctional, derived from non-chromaffin cells located in the neck and at the base of the skull. It is often necessary to exclude it in patients with early and severe arterial hypertension, or with therapeutic refractoriness. This case shows an example of a patient with arterial hypertension that was very difficult to control, whose etiological investigation revealed the presence of a cervical paraganglioma.
Downloads
References
Erickson D, Kudva Y, Ebersold M, Thompson G, Grant C, van Heerden J et al. Benign Paragangliomas: Clinical Presentation and Treatment Outcomes in 236 Patients. The Journal of Clinical Endocrinology & Metabolism. 2001;86(11):5210-5216.
Tsirlin A, Oo Y, Sharma R, Kansara A, Gliwa A, Banerji M. Pheochromocytoma: A review. Maturitas. 2014;77(3):229-238.
Fishbein L. Pheochromocytoma and Paraganglioma. Hematology/Oncology Clinics of North America. 2016;30(1):135- 150.
Pappachan J, Tun N, Arunagirinathan G, Sodi R, Hanna F. Pheochromocytomas and Hypertension. Current Hypertension Reports.2018;20(1).
Lenders J, Duh Q, Eisenhofer G, Gimenez-Roqueplo A, Grebe S, Murad M et al. Pheochromocytoma and Paraganglioma: An Endocrine Society Clinical Practice Guideline. The Journal of Clinical Endocrinology & Metabolism. 2014;99(6):1915-1942.
Plouin PF, Amar L, Dekkers OM, et al. European Society of Endocrinology Clinical Practice Guideline for long-term followup of patients operated on for a phaeochromocytoma or a paraganglioma. Eur J Endocrinol. 2016;174:G1–G10.
Timmers H, Chen C, Carrasquillo J, Whatley M, Ling A, Eisenhofer G et al. Staging and Functional Characterization of PheochromocytomaandParagangliomaby18F-Fluorodeoxyglucose (18F-FDG) Positron Emission Tomography. JNCI: Journal of the National Cancer Institute. 2012;104(9):700-708.
Majtan B, Zelinka T, Rosa J, et al. Long-term effect of adrenalectomy on cardiovascular remodeling in patients with pheochromocytoma. J Clin Endocrinol Metab. 2016;102:1208–17.